Effect of Pulmonary Function Tests on Peri-Operative Outcomes After Robotic-Assisted Pulmonary Lobectomy: Retrospective Analysis of 234 Consecutive Cases
Kathryn Rodriguez1, Frank O. Velez-Cubian1, Wei Wei Zhang1, Matthew R. Thau1, Jacques-Pierre Fontaine2, Joseph R. Garrett2, Carla C. Moodie2, Lary A. Robinson2, Eric M. Toloza2, 1University of South Florida College of Medicine, Tampa, FL, 2Moffitt Cancer Center, Tampa, FL
OBJECTIVE: The need to increase patient safety and expand surgical options for lung cancer patients with poor pulmonary function is evident in literature. Pulmonary function tests have been found to be predictors of respiratory complications after lung resection in thoracotomy procedures yet not in video-assisted thoracoscopic procedures. We seek to determine the predictive role of forced expired volume in one second (FEV1) and diffusion capacity for carbon monoxide (DLCO) for respiratory complications after robotic-assisted pulmonary lobectomy.
METHODS: We retrospectively analyzed preoperative pulmonary function tests and postoperative respiratory complications of 234 consecutive patients who underwent robotic-assisted pulmonary lobectomy at a single institution over 33 months. Logistic regression was used to determine whether DLCO and FEV1 are significant predictors of respiratory complications.
RESULTS: Of 234 consecutive patients (mean age 67 ±10yrs) undergoing robotic-assisted lobectomy, mean percent DLCO was 76% ±18% and mean percent FEV1 was 87% ±22%. There were 65/234 (28%) patients with postoperative respiratory complications. Logistic regression (see Figure) revealed that neither DLCO nor FEV1 were significant predictors of respiratory complications (p>0.05).
CONCLUSIONS: Pulmonary function is not a significant predictor of respiratory complications after robotic-assisted lobectomy. Thus, our study suggests that robotic-assisted pulmonary lobectomy is feasible and safe for patients with impaired pulmonary function.