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Trends in Demographics, Interventions, and Outcomes in Pediatric Patients with Hypertrophic Cardiomyopathy
Nehal Dhaduk, BS1, Aakash Shah, BS1, Emaad Siddiqui, MD2, Alexis K. Okoh, MD3, Justin Sambol, MD1
1NJMS, Newark, NJ, USA, 2NYU Langone Medical Center, NYC, NY, USA, 3NBI Medical Center, Newark, NJ, USA

OBJECTIVE: Pediatric hypertrophic cardiomyopathy (HCM)is a rare, but serious disorder that is underrepresented in the literature. We investigated demographics, reasons for hospitalization, procedural utilization, and outcomes in young HCM patients.
METHODS: The Kids’ Inpatient Database was queried from 2003-2016 for patients less than 21-years-old with a diagnosis of HCM. Trends in patient demographics, hospital characteristics, and outcome measures were analyzed.
RESULTS: We identified a total of 3075 pediatric cases of HCM with an average age of 8.76 +/- 7.56 years. There was a statistically significant increase in the HCM admissions from 2003 to 2016 (p=0.049). The majority of patients were 12 to 17-years-old (26.3%), male (61.6%), and white (40.8%). In terms of hospital demographics, most patients were admitted to large bed-size hospitals (69.7%), hospitals in the South (35.9%), and urban-teaching hospitals (88.7%). The most common reasons for admission were ventricular tachycardia (VT) (5.4%) and acute heart failure (AHF) (3.5%); AHF and VT admissions had the highest mortality (6.2%). The most common interventions performed were ICD placement (7.7%) and septal myomectomy (6.4%); septal myomectomy (3.1%) had the highest mortality of the interventions analyzed. Overall mortality rate and average length of stay was 3.2% and 11.45 +/- 24.69 days, respectively. We found no significant trend in mortality.
CONCLUSIONS: The number of pediatric HCM patients being admitted to the hospital has increased across the country. VT is the most common reason for hospitalization. Mortality amongst HCM patients has been similar over recent years with AHF and VT having the greatest mortality rates.


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